Publications

Harcombe WR, Betts A, Shaprio JW, Marx CJ. (2016) Adding biotic complexity alters the metabolic benefits of mutualism. Evolution. 70:1871-1881. pdf

Chacón JM, Harcombe WR. (2016) Antimicrobials: Constraints on microbial warfare. Nature Microbiology 1:16225. pdf

Douglas SM, Chubiz LM, Harcombe WR, Ytreberg FM, Marx CJ. (2016) Parallel mutations Result in a wide range of cooperation and community consequences in a two-species consortium. PLoS One 11:e0161837. pdf

Chubiz LM, Granger BR, Segre D, Harcombe WR. (2015) Species interactions differ in their genetic robustness. Frontiers in Microbiology 6:271. pdf

Harcombe, W.R.*, Riehl, W*., Dukovski, I., Granger, B.R. Betts, A., Lang, A.H. Bonilla, G., Kar, A., Leiby, N., Mehta, P., Marx, C.J., Segre, D. (2014) Predicting the spatio-temporal dynamics of microbial community metabolism. Cell Reports 7(4):1104-1115. pdf

Plucain, J. Hindre, T., Le Gac M., Tenaillon, O., Cruvioller, S., Medigue, C., Leiby. N., Harcombe, W.R., Marx, C.J., Lenski, R., Schnedier, D. (2014) Epistasis and allele specificity in the emergence of a stable polymorphism in Escherichia coli. Science 343(6177):1366-1369. pdf

Chubiz, L. Douglas, S. Harcombe, W.R. (2014) Combining engineering and evolution to create metabolic mutualisms between species. Methods in Molecular Biology 1151:39-47.

Harcombe, W.R. Delaney, N.F., Leiby, N., Klitgord, N. & Marx, C.J. (2013) The ability of flux balance analysis to predict evolution of central metabolism scales with the initial distance to the optimum. PLoS: Computional Biology. 9(6), e1003091.  pdf

Leiby, N.L., Harcombe, W.R., Marx, C.J. (2012) Multiple long-term, experimentally-evolved population of Escherichia coli acquire dependence upon citrate as an iron chelator for optimal growth on glucose. BMC Evolutionary Biology. 12:151.  pdf

Harcombe, W.R. (2010) Novel cooperation experimentally evolved between species. Evolution. 64(7) 2166-2172.*  pdf

                        *Highlighted in Nature 464: 145.

Harcombe, W.R., Springman, R. & Bull, J.J. (2009) Compensatory evolution for a gene deletion is not limited to its immediate functional network. BMC Evolutionary Biology. 9(1):106.  pdf

Bull, J.J. & Harcombe, W.R. (2009) Dynamical constraints on the cooperative evolution of cross-feeding. PLoS: One. 4(1):e4115.  pdf

Cowperthwaite, M.C., Economo, E.P., Harcombe, W.R., Miller, E.L., & Meyers, L.A. (2008) A simple rule shapes phenotypic evolution. PLoS: Computational Biology. 4(7):e1000110.  pdf

Weeks A.R., Turelli M., Harcombe W.R., Reynolds K.T., & Hoffmann A.A. (2007) From parasite to mutualist: Rapid evolution of Wolbachia in natural populations of Drosophila. PLoS: Biology. 17:5  pdf

Pfennig, D.W., Harper, G.R., Brumo, A.F., Harcombe, W.R. & Pfennig, K.S. (2007) Population differences in predation on Batesian mimics in allopatry with their model: selection against mimics is strongest when they are common. Behavioral Ecology and Sociobiology 61, 505-511.  pdf

Harcombe, W.R. & Bull, J.J. (2005) Impact of phages on a two-species bacterial community.  Applied and Environmental Microbiology 71, 5254-5259.  pdf

Harcombe, W.R. & Hoffmann, A. (2004) Wolbachia effects in Drosophila melanogaster: in search of fitness benefits. Journal of Invertebrate Pathology 87, 45-50.  pdf

Pfennig, D.W., Harcombe, W.R. & Pfennig, K.S. (2001) Evolution of mimicry in snakes. Nature 410, 323.  pdf